American Ginseng Basics

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Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview

0 0 The first issue of Natural Product Reports in 2015 will publish a comprehensive review regarding ginseng’s anti-cancer effects and underlying mechanisms. Here we summarize this review as follows:...

Protopanaxadiol

Pharmacological Review of Ginsenoside Dammarane Saponin Rh2

3 0 Please download here. Related PostsAntiallergic activity of ginsenoside Rh2 Rb1 prevents osteoporosis by inhibiting osteoclastogenesis PPD induces apoptosis of glioma cells Rh2 improves insulin sensitivity Antiestrogenic effect of...

081

Pharmacological Review of Ginsenoside Dammarane Saponin Rg1

0 0 Please download here. Related PostsRb1 prevents inflammation and apoptosis in human articular chondrocytes Anti-arthritic effect of ginsenoside Rb1 PPT improves hematopoiesis in myelosuppression mice Rh2 induces β-cell regeneration...

042

Pharmacological Review of Ginsenoside Dammarane Saponin Rb1

0 0 Please download here. Related PostsGinsenoside Rb1 attenuates activated microglia-induced brain damage Ginsenoside Rb1 prevents neuronal injury and stimulates growth of axons and dendrites Protective effects of ginsenoside Rb1...

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Pharmacological Review of Aglycon Dammarane Sapogenin (AGS) – Protopanaxatriol (PPT)

0 0 Please download here. Related PostsGinsenoside Rb1 improves postoperative fatigue syndrome Ginsenoside rb1 protects the heart from hypoxia/ischemia Ginsenosides Rg1 and Rb1 are the major ingredients of Fufang Danseng...

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Pharmacological Review of Aglycon Dammarane Sapogenin (AGS) – Protopanaxadiol (PPD)

0 0 Please download here.   Related PostsDripping pill can be an effective drug delivery method for oral dammarane sapogenins Ginsenosides Rg1 activates neural stem cells Immunomodulation by ginsenoside Rg1...

008

Antiallergic activity of ginsenoside Rh2

0 0 The antiallergic activities of ginsenosides, which were isolated from acid-treated ginseng (Panax ginseng, Araliaceae), and their metabolites by human intestinal bacteria were measured. Ginsenoside Rh2, which is a...

107

Rb1 prevents osteoporosis by inhibiting osteoclastogenesis

0 0 Ginsenosides, the main active components of ginseng, have been reported possessing anti-osteoporosis activity in ovariectomized rats. However, the active ingredient and the mechanisms underlying the anti-osteoporosis activity of...

028

PPD induces apoptosis of glioma cells

0 0 20S-Protopanaxadiol (PPD) is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponins. In the present study, PPD was used to induce cytotoxicity for two human glioma cell lines,...

132

Rh2 improves insulin sensitivity

0 0 Ginsenoside Rh2, one of the ginsenosides contained in the Panax ginseng root, was employed to screen the effect on insulin resistance of rats induced by a diet containing...

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Panax is a genus of perennial herbs, with two species in eastern North America and perhaps 5-10 species in Asia. American ginseng occurs from southern Ontario and south-western Quebec south to Oklahoma, Louisiana, and northern Florida.

The un-branched, erect stems of American ginseng arise from a short rhizome and an elongated tuberous root. The root is 1-3 cm thick and 5-10 cm long, spindle-shaped, and often forked. The roots of older plants become branched and acquire prominent circular wrinkles; they are slightly aromatic, and have a sweetish, somewhat bitter taste. Mature plants are 20-70 cm tall, with a whorl of three or four long-stalked, palmate leaves, each generally with five large leaflets, of which the upper three are larger than the lower two. In mid-summer, 6-20 small, yellowish flowers are borne on a short stalk arising from the centre of leaf attachment at the top of the stem. Fruits begin to ripen at the end of July and mature to a deep red color.

Reproduction is entirely by seed. Seeds are produced by plants more than 3 years old with up to 150 being generated by a single plant. However, commonly, only a few seeds are matured by wild plants. Once a seedling of American ginseng has become established, its life expectancy is over 20 years, and some plants have been reported to live to at least 60 years of age.

Ginseng occurs in colonies of a few to hundreds of plants in rich, shady, deciduous forests, in deep leaf litter. Sites are frequently on northern or north-eastern cool rocky slopes, commonly in areas with limestone outcrops in damp but well-drained soils. American ginseng thrives in 75% shade, and even shadier locations in the southern limits of its range. Clear-cutting of virgin forests and over-harvesting have drastically reduced the size of wild populations.

American Ginseng Basics
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